Dementia with Lewy bodies (DLB): systemic treatments

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Dementia with Lewy bodies (DLB): systemic treatments. Transcranial magnetic stimulation (TMS). Fully referenced neurology checklist.

Treatment of depression

  • Selective serotonin reuptake inhibitors (SSRIs) e.g. Citalopram
  • Serotonin norepinephrine reuptake inhibitors (SNRIs) e.g. Venlafaxine
  • Transcranial magnetic stimulation (TMS)
  • Electroconvulsive therapy (ECT)

Treatment of orthostatic hypotension

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Treatment of detrusor instability

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Treatment of erectile dysfunction

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Treatment of gait impairment

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Treatment of excessive sweating

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Drugs to avoid

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References

  1. McKeith IG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology 1996; 47:1113-1124.
  2. McKeith IG, Dickson DW, Lowe J, et al. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium. Neurology 2005; 65:1863-1872.
  3. Hanagasi HA, Bilgiç B, Emre M. Neuroimaging, biomarkers, and management of dementia with Lewy bodies. Front Neurol 2013; 4:151.
  4. Taylor JP, McKeith IG, Burn DJ, et al. New evidence on the management of Lewy body dementia. Lancet Neurol 2020; 19:157-169.
  5. Boot BP, McDade EM, McGinnis SM, Boeve BF. Treatment of dementia with Lewy Bodies. Curr Treat Options Neurol 2013; 15:738-764.

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