Dementia with Lewy bodies (DLB): neurological treatments
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Dementia with Lewy bodies (DLB): neurological treatments. A third of cases demonstrate Levodopa-responsiveness. Fully referenced neurology checklist.
Levodopa
- A third of cases demonstrate Levodopa-responsiveness
- Younger patients are more likely to respond
Treatment of cognitive impairment
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Treatment of visual hallucinations
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Treatment of behavioural symptoms
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Treatment of REM sleep behaviour disorder (RBD)
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Treatment of excessive daytime sleepiness (EDS)
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Drugs to avoid
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References
- McKeith IG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology 1996; 47:1113-1124.
- McKeith IG, Dickson DW, Lowe J, et al. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium. Neurology 2005; 65:1863-1872.
- Hanagasi HA, Bilgiç B, Emre M. Neuroimaging, biomarkers, and management of dementia with Lewy bodies. Front Neurol 2013; 4:151.
- Taylor JP, McKeith IG, Burn DJ, et al. New evidence on the management of Lewy body dementia. Lancet Neurol 2020; 19:157-169.
- Molloy S, McKeith IG, O'Brien JT, Burn DJ. The role of levodopa in the management of dementia with Lewy bodies. JNNP 2005; 76:1200-1203.
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