Dementia with Lewy bodies (DLB): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Dementia with Lewy bodies (DLB): clinical features. Dementia, Fluctuating cognition. Fully referenced neurology checklist.
Essential and core clinical features of DLB
- Dementia
- Fluctuating cognition
- Recurrent well-formed visual hallucinations
- REM sleep behaviour disorder (RBD) without atonia
- Spontaneous Parkinsonism
Autonomic features
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Psychiatric features
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Corticobasal syndrome (CBS) presentation
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Other supportive features
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Other presentations
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Old synonyms
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References
- McKeith IG, Boeve BF, Dickson DW, et al. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology 2017; 89:88-100.
- McKeith IG, Dickson DW, Lowe J, et al. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium. Neurology 2005; 65:1863-1872.
- Outeiro TF, Koss DJ, Erskine D, et al. Dementia with Lewy bodies: an update and outlook. Mol Neurodegener 2019; 14:5.
- Ferman TJ, Boeve BF, Smith GE, et al. Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies. Neurology 2011; 77:875-882.
- Munechika T, Fujishiro H, Okuda M, et al. Rapid eye movement sleep without atonia may help diagnose Lewy body disease in middle-aged and older patients with somatic symptom disorder. Psychogeriatrics 2017; 17:61-69.
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