Craniopharyngioma

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Craniopharyngioma. These are tumours arising from Rathke’s pouch remnants. Fully referenced neurology checklist.

Pathology

  • These are tumours arising from Rathke’s pouch remnants
  • They are found in the sellar or parasellar regions

Pathogenesis

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Epidemiological features

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Classification

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Neurological features

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Psychiatric features

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Systemic features

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Endocrine features

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Differential diagnosis

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Magnetic resonance imaging (MRI) features

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Computed tomography (CT) features

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Treatment

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Investigational treatments

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References

  1. Meyer S, Shah SN, Dancel-Manning K, Wang Y, Young M, Agrawal N. A case-based review of adult-onset craniopharyngioma. Front Endocrinol (Lausanne) 2025; 16:1527161.
  2. Alboqami MN, Khalid S Albaiahy A, et al. Craniopharyngioma: a comprehensive review of the clinical presentation, radiological findings, management, and future perspective. Heliyon 2024; 10:e32112.
  3. Pires de Oliveira Neto C, Nascimento GC, Damianse SDSP, Faria MDS. Recent advances in craniopharyngioma pathophysiology and emerging therapeutic approaches. Front Endocrinol (Lausanne) 2025; 16:1562942.
  4. Trifanescu R, Ansorge O, Wass JA, Grossman AB, Karavitaki N. Rathke's cleft cysts. Clin Endocrinol (Oxf) 2012; 76:151-160.
  5. Zada G. Rathke cleft cysts: a review of clinical and surgical management. Neurosurg Focus 2011; 31:E1.
  6. And 2 more. Subscribe to see the full list

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