Cerebral amyloid angiopathy (CAA): Boston diagnostic criteria

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cerebral amyloid angiopathy (CAA): Boston diagnostic criteria. Transient focal neurological deficits. Fully referenced neurology checklist.

Boston criteria version 2.0 for definite CAA: at post-mortem

  • Transient focal neurological deficits
  • Cognitive impairment or dementia
  • Spontaneous intracerebral haemorrhage (ICH)
  • Convexity subarachnoid haemorrhage
  • Vasculopathy
  • No other diagnostic lesions

Boston criteria version 2.0 for probable CAA

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References

  1. Charidimou A, Boulouis G, Frosch MP, et al. The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study. Lancet Neurol 2022; 21:714-725.

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