Autism spectrum disorders (ASD): risk factors
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Autism spectrum disorders (ASD): risk factors. This is the main genetic risk factor. Fully referenced neurology checklist.
PTEN gene mutation
- This is the main genetic risk factor
- It is part of the mTOR signaling pathway
Neurological risk factors: epilepsy
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Neurological risk factors: others
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Other risk factors
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References
- Berg AT, Dobyns WB. Progress in autism and related disorders of brain development. Lancet Neurol. 2015; 14:1069-1070.
- Pearce JM. Kanner’s infantile autism and Asperger’s syndrome. JNNP 2005; 76:205.
- Sundelin HE, Larsson H, Lichtenstein P, et al. Autism and epilepsy: a population-based nationwide cohort study. Neurology 2016; 87:192-197.
- Besag FM. Epilepsy in patients with autism: links, risks and treatment challenges. Neuropsychiatr Dis Treat 2017; 14:1-10.
- Jeste SS. The neurology of autism spectrum disorders. Curr Opin Neurol 2011; 24:132-139.
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