Autism spectrum disorders (ASD): management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Autism spectrum disorders (ASD): management. Delayed or absent spoken language, Unawareness of others. Fully referenced neurology checklist.

Monitor for indicators of development of autism

  • Delayed or absent spoken language
  • Unawareness of others
  • Impaired imagination
  • Lack of interest in play
  • Abnormal language prosody
  • Unusual vocabulary for age
  • Unusual relationships with adults
  • Difficulty coping with change
  • Difficulty making friends
  • Rigid thinking
  • Narrow interests

Medical management

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Management of core impairments

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Investigational treatments

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References

  1. Assessment, diagnosis and clinical interventions for children and young people with autism spectrum disorders. A national clinical guideline. SIGN Guideline 98. July 2007.
  2. Takarae Y, Minshew NJ, Luna B, Sweeney JA. Oculomotor abnormalities parallel cerebellar histopathology in autism. JNNP 2004; 75:1359-1361.
  3. Hirota T, King BH. Autism spectrum disorder: a review. JAMA 2023; 329:157-168.  
  4. Pickles A, Le Couteur A, Leadbitter K, et al. Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial. Lancet 2016; 388:2501-2509.
  5. Wong CM, Tan CS, Koh HC, et al. Folinic acid as a treatment for autism in children: a within-subjects open-label study on safety and efficacy. Int J Dev Neurosci 2025; 85:e10402.
  6. And 1 more. Subscribe to see the full list

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