Autism spectrum disorders (ASD): clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Autism spectrum disorders (ASD): clinical features. ASD affects about 2.3% of children and 2.2% of adults in the United States.

Epidemiology

  • ASD affects about 2.3% of children and 2.2% of adults in the United States
  • The prevalence is increasing

Key early clinical features

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Motor features

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Neurological features

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Sleep-related features

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Psychiatric features

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Gastrointestinal features

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Other features

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Pathological features

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Differential diagnosis: childhood disintegrative disorder (CDD)

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References

  1. Hirota T, King BH. Autism spectrum disorder: a review. JAMA 2023; 329:157-168. 
  2. Maski KP, Jeste SS, Spence SJ. Common neurological co-morbidities in autism spectrum disorders. Curr Opin Pediatr 2011; 23:609-615.
  3. Dziuk MA, Gidley Larson JC, Apostu A, Mahone EM, Denckla MB, Mostofsky SH. Dyspraxia in autism: association with motor, social, and communicative deficits. Dev Med Child Neurol 2007; 49:734-749.
  4. Pearce JM. Kanner’s infantile autism and Asperger’s syndrome. JNNP 2005; 76:205.
  5. Baron-Cohen S. The cognitive neuroscience of autism. JNNP 2004; 75: 945–948.
  6. And 15 more. Subscribe to see the full list

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