Anti GFAP autoimmune encephalitis: pathology
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti GFAP autoimmune encephalitis: pathology. This is an autoimmune astrocytopathy. Fully referenced neurology checklist.
Pathology
- This is an autoimmune astrocytopathy
- It causes a meningoencephalomyelitis
- It is associated with HLA-A*3303 and HLA-DPB1*0501
Possible triggers
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Associated neoplasms
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Associated autoimmune disorders
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Antibodies that may overlap with anti GFAP
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Acronym
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References
- Fang B, McKeon A, Hinson SR, et al. Autoimmune glial fibrillary acidic protein astrocytopathy: a novel meningoencephalomyelitis. JAMA Neurol 2016; 73:1297-1307.
- Flanagan EP, Hinson SR, Lennon VA, et al. Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: analysis of 102 patients. Ann Neurol 2017; 81:298-309.
- Shu Y, Long Y, Chang Y, et al. Brain immunohistopathology in a patient with autoimmune glial fibrillary acidic protein astrocytopathy. Neuroimmunomodulation 2018; 25:1-6.
- Shu Y, Huang R, Li Q, et al. Autoimmune glial fibrillary acidic protein astrocytopathy is associated with HLA-A*3303 and HLA-DPB1*0501. Ann Neurol 2024; 95:901-906.
- Li J, Xu Y, Ren H, Zhu Y, Peng B, Cui L. Autoimmune GFAP astrocytopathy after viral encephalitis: a case report. Mult Scler Relat Disord 2018; 21:84-87.
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