Anti AMPAR autoimmune encephalitis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti AMPAR autoimmune encephalitis. The antibodies target AMPAR receptors. Fully referenced neurology checklist.
Pathology
- The antibodies target AMPAR receptors
- They are made up of tetramers of the glutamate receptors (GluR) types 1, 2, 3 or 4
Epidemiology
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Clinical features
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Associated tumours
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Investigations
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Treatment
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Acronym
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References
- Rosenfeld MR, Dalmau J. Anti-NMDA-receptor encephalitis and other synaptic autoimmune disorders. Curr Treat Options Neurol 2011; 13:324-332.
- Lee R, Buckley C, Irani SR, Vincent A. Autoantibody testing in encephalopathies. Pract Neurol 2012; 12:4-13.
- Vincent A, Bien CG, Irani SR, Waters P. Autoantibodies associated with diseases of the CNS: new developments and future challenges. Lancet Neurol 2011; 10:759-772.
- Dogan Onugoren M, Deuretzbacher D, Haensch CA, et al. Limbic encephalitis due to GABAB and AMPA receptor antibodies: a case series. JNNP 2015; 86:965-972.
- Joubert B, Kerschen P, Zekeridou A, et al. Clinical spectrum of encephalitis associated with antibodies against the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor: case series and review of the literature. JAMA Neurol 2015; 72:1163-1169.
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