Anti-AK5 antibody autoimmune encephalitis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti-AK5 antibody autoimmune encephalitis. This is caused by anti-adenylate kinase 5 antibody. Fully referenced neurology checklist.
Pathogenesis
- This is caused by anti-adenylate kinase 5 antibody
- This is a nucleoside monophosphate kinase
Pathological features
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Neurological features
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Psychiatric features
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Absent features
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Cerebrospinal fluid (CSF) analysis
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Magnetic resonance imaging (MRI) brain
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Outcome
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References
- Do LD, Chanson E, Desestret V, et al. Characteristics in limbic encephalitis with anti-adenylate kinase 5 autoantibodies. Neurology 2017; 88:514-524.
- Ng AS, Kramer J, Centurion A, et al. Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis. J Neuroimmunol 2015; 287:31-35.
- Vicino A, Loser V, Salvioni Chiabotti P, Brouland JP, Du Pasquier R. Anti-adenylate kinase 5 encephalitis with histologic evidence of CNS vasculitis. Neurol Neuroimmunol Neuroinflamm 2021; 8:e1010.
- McKeon-Makki I, McKeon A, Yang B, et al. Adenylate kinase 5 (AK5) autoimmune encephalitis: clinical presentations and outcomes in three new patients. J Neuroimmunol 2022; 367:577861.
