Zika virus infection (ZIKV): pathology
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Zika virus infection (ZIKV): pathology. This is an arthropod-borne virus: an arbovirus. Fully referenced neurology checklist.
Virology
- This is an arthropod-borne virus: an arbovirus
- It is a member of the family Flaviviridae
- It is neurotropic: it infects neural stem cells
Main transmission routes
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Other possible transmission routes
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Outbreaks
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Pathological features
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References
- de Paula Freitas B, de Oliveira Dias JR, Prazeres J, et al. Ocular findings in infants with microcephaly associated with presumed zika virus congenital infection in Salvador, Brazil. JAMA Ophthalmol 2016; doi: 10.1001/jamaophthalmol.2016.0267 (Epub ahead of print).
- Martines RB, Bhatnagar J, de Oliveira Ramos AM, et al. Pathology of congenital Zika syndrome in Brazil: a case series. Lancet 2016; 388:898-904.
- Li H, Saucedo-Cuevas L, Regla-Nava JA, et al. Zika virus infects neural progenitors in the adult mouse brain and alters proliferation. Cell Stem Cell 2016; pii: S1934-5909(16)30252-1 (Epub ahead of print).
- Besnard M, Lastere S, Teissier A, Cao-Lormeau V, Musso D. Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014. Euro Surveill 2014; 19(13).
- Turmel JM, Abgueguen P, Hubert B, et al. Late sexual transmission of Zika virus related to persistence in the semen. Lancet 2016; 387:2501.Roberts DJ, Frosch MP. Zika and histopathology in first trimester infections. Lancet 2016; 388:847-849.
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