Wake-up stroke
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Wake-up stroke. This occurs in 14-25% of ischemic strokes. It has worse outcomes and a higher mortality. Fully referenced neurology checklist.
Clinical features
- This occurs in 14-25% of ischemic strokes
- It has worse outcomes and a higher mortality
Magnetic resonance imaging (MRI)
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Treatment: thrombolysis
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Treatment: other types
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Wake-up stroke v daytime unknown time of onset stroke (UTOS)
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References
- Mackey J, Kleindorfer D, Sucharew H, et al. Population-based study of wake-up strokes. Neurology 2011; 76:1662-1667.
- Barreto AD, Martin-Schild S, Hallevi H, et al. Thrombolytic therapy for patients who wake-up with stroke. Stroke 2009; 40:827-832.
- Dorado L, Ahmed N, Thomalla G, et al. Intravenous thrombolysis in unknown-onset stroke: results from the safe implementation of treatment in Stroke-International Stroke Thrombolysis Registry. Stroke 2017; 48:720-725.
- Kim BJ, Lee S-H, Shin C-W, et al. Ischemic stroke during sleep: its association with worse early functional outcome. Stroke 2011; 42:1901-1906.
- Petkova M, Rodrigo S, Lamy C, et al. MR imaging helps predict tine from symptom onset in patients with acute stroke: implications for patients with unknown onset time. Radiology 2010; 257:782-792.
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