Silent brain infarcts (SBI)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Silent brain infarcts (SBI). These are five times more prevalent than stroke. Fully referenced neurology checklist.

Demographic features

  • These are five times more prevalent than stroke
  • They are found in about 10% of normal people in midlife
  • They are present in about 20% of people following acute ischaemic stroke
  • The prevalence is 35% if stroke is associated coronary heart disease

Distribution

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Risk factors

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Consequences

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Magnetic resonance imaging (MRI) differentials

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Treatment

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References

  1. Vermeer SE, Longstreth WT, Koudstaal PJ. Silent brain infarcts: a systematic review. Lancet Neurol 2007; 6:611-619.
  2. Das RR, Seshadri S, Beiser AS, et al. Prevalence and correlates of silent cerebral infarcts in the Framingham Offspring Study. Stroke 2008; 39:2929-2935.
  3. Tisserand M, Guennec LL, Touze E, et al. Prevalence of MRI-defined recent silent ischaemia and associated bleeding risk with thrombolysis. Neurology 2011; 76:1288-1295.
  4. Slark J, Bentley P, Sharma P. Silent brain infarction in the presence of systemic vascular disease. JRSM Cardiovasc Dis 2012; 1:cvd.2012.012002.
  5. Putaala J, Haapaniemi E, Kurkinen M, Salonen O, Kaste M, Tatlisumak T. Silent brain infarcts, leukoaraiosis, and long-term prognosis in young ischemic stroke patients. Neurology 2011; 76:1742-1749.
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