Varicella zoster (VZV) vasculopathy: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Varicella zoster (VZV) vasculopathy: management. Pleocytosis: this occurs in a third of cases. Fully referenced neurology checklist.
Cerebrospinal fluid (CSF) analysis: features
- Pleocytosis: this occurs in a third of cases
- VZV DNA: this is detected in 30% of cases
- Anti-VZV IgG: this is present in 90% of cases
Magnetic resonance imaging (MRI): infarcts
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Magnetic resonance imaging (MRI): vasculitis
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Treatment
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References
- Gilden D, Cohrs RJ, Mahalingam R, Nagel MA. Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatment. Lancet Neurol 2009; 8:731-740.
- Nagel MA, Cohrs RJ, Mahalingam R, et al. The varicella zoster virus vasculopathies: clinical, CSF, imaging, and virologic features. Neurology 2008; 70:853-860.
- Bakradze E, Kirchoff KF, Antoniello D, et al. Varicella zoster virus vasculitis and adult cerebrovascular disease. Neurohospitalist 2019; doi.org/10.1177/1941874419845732 (Epub ahead of print).
- Nagel MA, Jones D, Wyborny A. Varicella zoster virus vasculopathy: the expanding clinical spectrum and pathogenesis. J Neuroimmunol 2017; 308:112-117.
