Uraemic myopathy

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Uraemic myopathy. It usually develops in end-stage renal failure. It is usually in people on dialysis. Fully referenced neurology checklist.

Demographic features

  • It usually develops in end-stage renal failure
  • It is usually in people on dialysis
  • It is more frequent in females over the age of 60 years
  • The severity corresponds to the degree of renal impairment

Clinical features

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Pathogenic factors

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Differential diagnosis

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Blood tests

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Muscle biopsy

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Treatment

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References

  1. Campistol JM. Uremic myopathy. Kidney Int 2002; 62:1901-1913.
  2. Burn DJ, Bates D. Neurology and the kidney. JNNP 1998; 65:810-821. 
  3. Arnold R, Issar T, Krishnan AV, Pussell BA. Neurological complications in chronic kidney disease. JRSM Cardiovasc Dis 2016; 5:2048004016677687.
  4. Kaltsatou A, Sakkas GK, Poulianiti KP, et al. Uremic myopathy: is oxidative stress implicated in muscle dysfunction in uremia? Front Physiol 2015; 6:102. 
  5. Adeniyi O, Agaba EI, King M, Servilla KS, Massie L, Tzamaloukas AH. Severe proximal myopathy in advanced renal failure. Diagnosis and management. Afr J Med Med Sci 2004; 33:385-388.
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