Tuberculous meningitis (TBM): immune reconstitution inflammatory syndrome (IRIS)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Tuberculous meningitis (TBM): immune reconstitution inflammatory syndrome (IRIS). This develops in association with anti-retroviral (ARV) treatment of HIV.
Pathogenesis
- This develops in association with anti-retroviral (ARV) treatment of HIV
- It starts after a median of 14 days after treatment
Risk factors
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Clinical features
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Treatment
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Prevention
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References
- Marx GE, Chan ED. Tuberculous meningitis: diagnosis and treatment overview. Tuberc Res Treat 2011; 2011:798764.
- Thwaites GE, van Toorn R, Schoeman J. Tuberculous meningitis: more questions, still too few answers. Lancet Neurol 2013; 12:999–1010.
- van Toorn R, Rabie H, Dramowski A, Schoeman JF. Neurological manifestations of TB-IRIS: a report of 4 children. Eur J Paediatr Neurol 2012; 16:676-682.
Related checklists
- Tuberculosis (TB): central nervous system types
- Tuberculous meningitis (TBM): clinical features
- Tuberculous meningitis (TBM): complications
- Tuberculosis (TB): calvarial
- Tuberculosis (TB): intracranial tuberculoma
- Tuberculosis (TB): brain abscess and encephalopathy
- Tuberculosis (TB): Pott’s disease of the spine
- Tuberculosis (TB): radiculomyelitis
- Tuberculosis (TB): spinal meningitis
- Tuberculous meningitis (TBM): CSF analysis
- Tuberculous meningitis (TBM): treatment
- Isolated tuberculosis myositis (ITBM)
