Tuberculosis (TB): brain abscess and encephalopathy

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Tuberculosis (TB): brain abscess and encephalopathy. These are encapsulated pus containing lesions. Fully referenced neurology checklist.

Tuberculous brain abscess

  • These are encapsulated pus containing lesions
  • They are solitary or multiple lesions
  • They are frequently multi-loculated
  • They have thicker walls than pyogenic brain abscesses
  • They form from tubercular granulomas or tuberculous meningitis
  • They are larger and more rapidly progressive than tuberculomas
  • Brain imaging shows a liquid centre with marked surrounding oedema

Tuberculous encephalopathy (TBE)

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References

  1. Garg RK. Tuberculosis of the central nervous system. Postgrad Med J 1999; 75:133-140.
  2. Rock RB, Olin M, Baker CA, Molitor TW, Peterson PK. Central nervous system tuberculosis: pathogenesis and clinical aspects. Clin Microbiol Rev 2008; 21:243-261.
  3. Cherian A, Thomas SV. Central nervous system tuberculosis. Afr Health Sci 2011; 11:116-127.

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