Transient topographical amnesia (TTA)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Transient topographical amnesia (TTA). This is transient amnesia of spatial orientation in healthy people. Fully referenced neurology checklist.

Description

  • This is transient amnesia of spatial orientation in healthy people
  • Subjects are unable to find their way in familiar or unfamiliar surroundings
  • This is due to an inability to use environmental landmarks to find their route
  • There is usually no associated brain damage
  • It usually occurs in healthy middle-aged women

Causes

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Clinical features

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Exclusion criteria

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Investigations

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Differential diagnoses

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References

  1. Naranjo-Fernández C, Arjona A, Quiroga-Subirana P, et al. Transient topographical amnesia: a description of a series of eight cases. Rev Neurol 2010; 50:217-220.
  2. Stracciari A, Lorusso S, Pazzaglia P. Transient topographical amnesia. JNNP 1994; 57:1423–1425.
  3. Cammalleri R, Gangitano M, D'Amelio M, Raieli V, Raimondo D, Camarda R. Transient topographical amnesia and cingulate cortex damage: a case report. Neuropsychologia 1996; 34:321-326.
  4. Yohannan DG, Watson RS, John NJ. 'Lost my way' - transient topographic amnesia: a bizarre manifestation of migraine. Ann Indian Acad Neurol 2018; 21:341-343.
  5. Mazzoni M, Del Torto E, Vista M, Moretti P. Transient topographical amnesia: a case report. Ital J Neurol Sci 1993; 14:633-636.

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