Focal retrograde amnesia (FRA)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Focal retrograde amnesia (FRA). It is caused by damage to the temporal lobes. Fully referenced neurology checklist.

Pathology

  • It is caused by damage to the temporal lobes
  • The hippocampal formation is relatively spared

Neurological causes

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Psychiatric causes

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Clinical features

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Magnetic resonance imaging (MRI) brain

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References

  1. Parkin AJ. Focal retrograde amnesia: a multi-faceted disorder? Acta Neurol Belg 1996; 96:43-50.
  2. Stracciari A, Fonti C, Guarino M. When the past is lost: focal retrograde amnesia: focus on the “functional” form. Behav Neurol 2008; 20:113-125.
  3. Sehm B, Frisch S, Thöne-Otto A, Horstmann A, Villringer A, Obrig H. Focal retrograde amnesia: voxel-based morphometry findings in a case without MRI lesions. PLoS One 2011; 6:e26538.
  4. Stracciari A, Mattarozzi K, Fonti C, Guarino M. Functional focal retrograde amnesia: lost access to abstract autobiographical knowledge? Memory 2005; 13:690-699.
  5. Hornberger M, Mohamed A, Miller L, Watson J, Thayer Z, Hodges JR. Focal retrograde amnesia: Extending the clinical syndrome of transient epileptic amnesia. J Clin Neurosci 2010; 17:1319-1321.
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