Thrombolysis: bleeding risk prediction tools

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Thrombolysis: bleeding risk prediction tools. History of diabetes or blood glucose >200mg/dL, Pre-treatment NIHSS. Fully referenced neurology checklist.

The HAT score: items

  • History of diabetes or blood glucose >200mg/dL
  • Pre-treatment NIHSS
  • Early visible hypodensity on early CT

The SEDAN score: items

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The ASTRAL score: items

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The DRAGON score: items

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The SITS-SICH score: items

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The TURN score: items

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Acronyms

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References

  1. Lou M, Safdar A, Mehdiratta M, et al. The HAT score: a simple grading scale for predicting haemorrhage after thrombolysis. Neurology 2008; 71:1417-1423.
  2. Strbian D, Engelter S, Michel P, et al. Symptomatic intracranial hemorrhage after stroke thrombolysis: the SEDAN score. Ann Neurol 2012; 71:634-641.
  3. Ntaios G, Faouzi M, Ferrari J, Lang W, Vemmos K, Michel P. An integer-based score to predict functional outcome in acute ischemic stroke: the ASTRAL score. Neurology 2012; 78:1916-1922.
  4. Ntaios G, Gioulekas F, Papavasileiou V, Strbian D, Michel P. ASTRAL, DRAGON and SEDAN scores predict stroke outcome more accurately than physicians. Eur J Neurol 2016; doi: 10.1111/ene.13100 (Epub ahead of print).
  5. Cooray C, Mazya M, Bottai M, et al. External validation of the ASTRAL and dragon scores for prediction of functional outcome in stroke. Stroke 2016; 47:1493-1499. 
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