Tardive dyskinesia: treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Tardive dyskinesia: treatment. Avoid provoking drugs if possible, Prescribe the lowest drug dose required. Fully referenced neurology checklist.

Prevention

  • Avoid provoking drugs if possible
  • Prescribe the lowest drug dose required
  • Taper the dose at the earliest sign of dyskinesia: do not stop abruptly

Use or switch to atypical neuroleptics

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Evidenced drug treatments

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Insufficient-evidenced drug treatments

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Novel drug treatments

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Insufficient-evidenced non-drug treatments

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Contraindicated drug treatments

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References

  1. Bhidayasiri R, Fahn S, Weiner WJ, et al. Evidence-based guideline: treatment of tardive syndromes: report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology 2013; 81:463-469. 
  2. Aia PG, Revuelta GJ, Cloud LJ, Factor SA. Tardive dyskinesia. Curr Treat Options Neurol 2011; 13:231-241.
  3. Bhidayasiri R, Boonyawairoj S. Spectrum of tardive syndromes: clinical recognition and management. Postgrad Med J 2011; 87:132-141.
  4. Glazer WM, Morgenstern H, Schooler N, Berkman CS, Moore DC. Predictors of improvement in tardive dyskinesia following discontinuation of neuroleptic medication. Br J Psychiatry 1990; 157:585–592.
  5. Waln O, Jankovic J. An update on tardive dyskinesia: from phenomenology to treatment. Tremor Other Hyperkinet Mov (N Y) 2013; 3: tre-03-161-4138-1.
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