Systemic vasculitic peripheral neuropathy (PN): features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Systemic vasculitic peripheral neuropathy (PN): features. The neuropathy is rapid onset except in some elderly. Fully referenced neurology checklist.

Onset and course

  • The neuropathy is rapid onset except in some elderly
  • It may follow a relapsing course

Neuropathy patterns

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Frequently affected mononeuropathy nerves

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Distal symmetrical neuropathy features

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Systemic features

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Nerve conduction studies (NCS)

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Pathologic features

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References

  1. Collins MP, Dyck JB, Gronseth GS, et al. Peripheral Nerve Society guideline on the classification, diagnosis, investigation, and immunosuppressive therapy of non-systemic vasculitic neuropathy: executive summary. J Peripher Nerv Syst 2010; 15:176-184.
  2. Gorson KC. Vasculitic neuropathies: an update. Neurologist 2007; 13:12-19.
  3. Matthew L, Talbot K, Love S, Puvanarajah S, Donaghy M. Treatment of vasculitic peripheral neuropathy: a retrospective analysis of outcome. Q J Med 2007; 100:41-51.
  4. Gorson KC. Therapy for vasculitic neuropathies. Curr Treat Options Neurol 2006; 8:105-117.

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