Non-systemic vasculitic peripheral neuropathy (PN)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Non-systemic vasculitic peripheral neuropathy (PN). This accounts for 10% of vasculitic neuropathy. Fully referenced neurology checklist.
Clinical features
- This accounts for 10% of vasculitic neuropathy
- The average onset age is 60 years
- Women account for 60% of cases
- The features are similar to systemic vasculitis but the prognosis is better
- Relapses may occur: especially if only steroid treatment was administered
Differential diagnosis
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Investigations
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First line treatment
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Maintenance treatment
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Treatment of refractory cases
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Treatments of unproven benefit
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Monitoring indices
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References
- Vrancken AFJE, Hughes RAC, Said G, Wokke JHJ, Notermans NC. Immunosuppressive treatment for non-systemic vasculitic neuropathy. Cochrane Database of Systematic Reviews 2007; Issue 1. Art. No.: CD006050.
- Matthew L, Talbot K, Love S, Puvanarajah S, Donaghy M. Treatment of vasculitic peripheral neuropathy: a retrospective analysis of outcome. Q J Med 2007; 100:41-51.
- Zhang T, Engelstad JK, Dyck PJB. Nonsystemic vasculitic neuropathy presenting as inflammatory demyelinating polyradiculoneuropathy. J Peripher Nerv Syst 2026; 31:e70158.
- Collins MP, Dyck JB, Gronseth GS, et al. Peripheral Nerve Society guideline on the classification, diagnosis, investigation, and immunosuppressive therapy of non-systemic vasculitic neuropathy: executive summary. J Peripher Nerv Syst 2010; 15:176-184.
