Super refractory status epilepticus (SRSE)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Super refractory status epilepticus (SRSE). Status epilepticus persisting after general anaesthesia. Fully referenced neurology checklist.
Definitions
- Status epilepticus persisting after general anaesthesia
- Status epilepticus recurring ≥24 hours after anaesthesia
Complication
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Non-drug treatment options
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Drug treatment options
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Interventional treatment options
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General care and monitoring
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References
- Shorvon S, Ferlisi M. The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol. Brain 2011; 134:2802-2818.
- Delaj L, Novy J, Ryvlin P, Marchi NA, Rossetti AO. Refractory and super-refractory status epilepticus in adults: a 9-year cohort study. Acta Neurol Scand 2017; 135:92-99.
- Hocker S, Nagarajan E, Rabinstein AA, Hanson D, Britton JW. Progressive brain atrophy in super-refractory status epilepticus. JAMA Neurol 2016; 73:1201-1207.
- Thakur KT, Probasco JC, Hocker SE, et al. Ketogenic diet for adults in super-refractory status epilepticus. Neurology 2014; 82:665-670.
- Appavu B, Vanatta L, Condie J, Kerrigan JF, Jarrar R. Ketogenic diet treatment for pediatric super-refractory status epilepticus. Seizure 2016; 41:62-65.
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