Refractory status epilepticus (RSE): treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Refractory status epilepticus (RSE): treatment. The dose is 3-5mg/kg bolus. Fully referenced neurology checklist.
Thiopentone
- The dose is 3-5mg/kg bolus
- Then 1-2mg/kg every 2-3 minutes until seizure control
Midazolam
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Propofol
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Emerging treatments: Ketamine
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Emerging treatments: others
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Treatment options for refractory complex partial status epilepticus
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Immunotherapy for NORSE
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Investigational treatments
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Goal of treatment
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Complications of treatments
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Acronym
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References
- Shorvon S, Ferlisi M. The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol. Brain 2011; 134:2802-2818.
- Hemphill S, McMenamin L, Bellamy MC, Hopkins PM. Propofol infusion syndrome: a structured literature review and analysis of published case reports. Br J Anaesth 2019; 122:448-459.
- López N, Correa A, Ammann R, Diettes A, Riveros R, Torres F. Propofol infusion syndrome in a refractory epileptic status case. Rev Chil Pediatr 2018; 89:384-390.
- Krajčová A, Waldauf P, Anděl M, Duška F. Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports. Crit Care 2015; 19:398.
- Mirrakhimov AE, Voore P, Halytskyy O, Khan M, Ali AM. Propofol infusion syndrome in adults: a clinical update. Crit Care Res Pract 2015; 2015:260385.
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