Subacute slerosing panencephalitis (SSPE): management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Subacute slerosing panencephalitis (SSPE): management. Parietooccipital typically, Corpus callosum, Basal ganglia. Fully referenced neurology checklist.

Magnetic resonance imaging (MRI): location of high intensity lesions

  • Parietooccipital typically
  • Corpus callosum
  • Basal ganglia
  • Cerebellum
  • Brainstem including isolated pontine involvement

Magnetic resonance imaging (MRI): other features

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Cerebrospinal fluid (CSF) analysis

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Other investigations

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Treatment

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References

  1. Öztürk M, Sığırcı A, Yakıncı C. MRI and MR spectroscopy findings of a case of subacute sclerosing panencephalitis affecting the corpus callosum. BMJ Case Rep 2015; pii: bcr2015209310.
  2. Tomoda A, Miike T, Miyagawa S, Negi A, Takeshima H. Subacute sclerosing panencephalitis and chorioretinitis. Brain Dev 1997; 19:55-57.
  3. Singhi P, Saini AG, Sankhyan N, Gupta P, Vyas S. Blindness, dancing extremities, and corpus callosum and brain stem involvement: an unusual presentation of fulminant subacute sclerosing panencephalitis. J Child Neurol 2015; 30:87-90.
  4. Upadhyayula PS, Yang J, Yue JK, Ciacci JD. Subacute sclerosing panencephalitis of the brainstem as a clinical entity. Med Sci (Basel) 2017; pii:E26.
  5. Kumar N, Ranjan A, Kumar A, Kumar B. Teaching NeuroImages: Isolated pontine involvement in subacute sclerosing panencephalitis. Neurology 2018; 91:e293-e294.
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