Subacute slerosing panencephalitis (SSPE): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Subacute slerosing panencephalitis (SSPE): clinical features. Poor vaccination history. Fully referenced neurology checklist.
Risk factors
- Poor vaccination history
- Measles acquired before the age of 5 years
- Associated HIV infection
Cerebral features
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Movement disorders
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Repetitive behaviours
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Vocalisations
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Peripheral nerve features
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Brainstem features
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Psychiatric features
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Ophthalmic features
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Ocular features
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Adult onset cases
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References
- Malhotra HS, Garg RK. Pearls & Oy-sters: Pisa syndrome: an unusual feature of adult-onset fulminant SSPE. Neurology 2015; 84:e12-e14.
- Garg RK. Subacute sclerosing panencephalitis. J Neurol 2008; 255:1861-1871.
- Mekki M, Eley B, Hardie D, Wilmshurst JM. Subacute sclerosing panencephalitis: clinical phenotype, epidemiology, and preventive interventions. Dev Med Child Neurol 2019; 61:1139-1144.
- Day GS, Tai P, Moharir M, Tang-Wai DF. Teaching NeuroImages: Recurrent SSPE presenting as Anton syndrome with cortical ribboning. Neurology 2015; 85:e141-e142.
- Tuncel D, Ozbek AE, Demirpolat G, Karabiber H. Subacute sclerosing panencephalitis with generalized seizure as a first symptom: a case report. Jpn J Infect Dis 2006; 59:317-319.
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