Stroke stem cell therapy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Stroke stem cell therapy. This is an investigational treatment for stroke. It has regenerative potential. Fully referenced neurology checklist.
Background
- This is an investigational treatment for stroke
- It has regenerative potential
Agents
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Routes of administration
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Benefits and risks
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References
- Kalladka D, Sinden J, Pollock K, et al. Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study. Lancet 2016; 388:787-796.
- Hess DC, Wechsler LR, Clark WM, et al. Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol 2017; 16:360-368.
- Marei HE, Hasan A, Rizzi R, et al. Potential of stem cell-based therapy for ischemic stroke. Front Neurol 2018; 9:34.
- Dulamea AO. The potential use of mesenchymal stem cells in stroke therapy-from bench to bedside. J Neurol Sci 2015; 352:1-11.
- Chung JW, Chang WH, Bang OY, et al. Efficacy and safety of intravenous mesenchymal stem cells for ischemic stroke. Neurology 2021; 96:e1012-e1023.
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