Secondary stroke prevention

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Secondary stroke prevention. See Neurochecklist: “Antiplatelet therapy”. Fully referenced neurology checklist.

Antiplatelets

  • See Neurochecklist: “Antiplatelet therapy”

Blood pressure reduction

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Statin therapy

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Smoking cessation: mechanisms

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Alcohol reduction

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Exercise

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Dietary control

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Other preventative measures

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Investigational preventative measures

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Acronym

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References

  1. Furie KL, Kasner SE, Adams RJ, et al. Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2011; 42:227-276.
  2. Derdeyn CP, Chimowitz MI, Lynn MJ, et al; Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Trial Investigators. Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial. Lancet 2014; 383:333-341. 
  3. Kleindorfer DO, Towfighi A, Chaturvedi S, et al. 2021 Guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association. Stroke 2021; 52:e364-e467. 
  4. Nassief A, Marsh JD. Statin therapy for stroke prevention. Stroke 2008; 39:1042-1048.
  5. Milionis HJ, Giannopoulos S, Kosmidou M, et al. Statin therapy after first stroke reduces 10-year stroke recurrence and improves survival. Neurology 2009; 72:1816-1822.
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