Statin myopathy: management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Statin myopathy: management. Concomitant use of risky drugs, Hypothyroidism, Myopathic CoQ10 deficiency. Fully referenced neurology checklist.

Contraindications and precautions with statins

  • Concomitant use of risky drugs
  • Hypothyroidism
  • Myopathic CoQ10 deficiency
  • Mitochondrial disease (except prescribed with CoQ10)

Indications for weekly CK monitoring

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Indications for stopping statins

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Indications for 6-week statin holiday

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Converting to alternative statins: indications

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Converting to alternative statins: process

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Treatment for myalgias

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References

  1. Sathasivam S, Lecky B. Statin induced myopathy. BMJ 2008; 337:a2286.
  2. Baker SK, Tarnopolsky MA. Statin myopathies: pathophysiologic and clinical perspectives. Clin Invest Med 2001; 24:258-272.
  3. Radcliffe KA, Campbell WW. Statin myopathy. Curr Neurol Neurosci Rep 2008; 8:66-72.
  4. Fernandez G, Spatz ES, Jablecki C, Phillips PS. Statin myopathy: a common dilemma not reflected in clinical trials. Cleve Clinic J Med 2011; 78:393-503.
  5. Siddiqi SA, Thompson PD. How do you treat patients with myalgia who take statins? Curr Atheroscler Rep 2009; 11:9-14.
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