Sporadic adult onset ataxia: neurological causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Sporadic adult onset ataxia: neurological causes. Neurosyphilis, Creutzfeldt Jakob disease (CJD). Fully referenced neurology checklist.

Chronic infections

  • Neurosyphilis
  • Creutzfeldt Jakob disease (CJD)
  • Lyme neuroborreliosis
  • Whipple’s disease

Sporadic degenerative

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Hereditary

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Synonyms for idiopathic types

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References

  1. Klockgether T. Sporadic ataxia with adult onset: classification and diagnostic criteria. Lancet Neurol 2010; 9:94-104.
  2. Abele M, Burk K, Schols L, et al. The aetiology of sporadic adult‐onset ataxia. Brain 2002; 125:961-968.
  3. Muzaimi MB, Thomas J, Palmer-Smith, Rosser L, et al. Population based study of late onset cerebellar ataxia in south east Wales. JNNP 2004; 75:1129-1134.
  4. van Gaalen J,  van de Warrenburg BPC. A practical approach to late-onset cerebellar ataxia: putting the disorder with lack of order into order. Postgrad Med J 2012; 88:407-417.
  5. Marmolino D, Manto M. Past, present and future therapeutics for cerebellar ataxias. Curr Neuropharmacol 2010; 8:41-61.
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