Spinocerebellar ataxia (SCA) summary of key features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Spinocerebellar ataxia (SCA) summary of key features. This is caused by mutations in the ataxin 1 (ATXN1) gene on chromosome 6p.
SCA1
- This is caused by mutations in the ataxin 1 (ATXN1) gene on chromosome 6p
- This is a CAG repeat expansion disorder
- It causes ophthalmoplegia and hypometric saccades
SCA2
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SCA3
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SCA4
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SCA5
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SCA6
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SCA7
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SCA8
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SCA9
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SCA10
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SCA11
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SCA12
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SCA13
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SCA14
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SCA15
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SCA16
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SCA17
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SCA18
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SCA19
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SCA20
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SCA21
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SCA22
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SCA23
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SCA24
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SCA25
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SCA26
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SCA27
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SCA28
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SCA29
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SCA30
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SCA31
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SCA32
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SCA33
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SCA34
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SCA35
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SCA36
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SCA37
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SCA38
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SCA39
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SCA40
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SCA41
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SCA42
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SCA43
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References
- Whaley NR, Fujioka S, Wszolek ZK. Autosomal dominant cerebellar ataxia type I: a review of the phenotypic and genotypic characteristics. Orphanet J Rare Dis 2011; 6:33.
- Bhidayasiri R, Waters MF, Giza CC. Neurological differential diagnosis. A Prioritized Approach. Blackwell Publishing Massachusetts 2005 p206-207.
- Manto MU. The wide spectrum of spinocerebellar ataxia. The Cerebellum 2005; 4:2-6.
- Gasser T, Finstererb J, Baetsc J, et al. EFNS guidelines on the molecular diagnosis of ataxias and spastic paraplegias. Eur J Neurol 2010, 17:179–188.
- Kim JS, Kim JS, Youn J, et al. Ocular motor characteristics of different subtypes of spinocerebellar ataxia: distinguishing features. Mov Disord 2013; 28:1271-1277.
Related checklists
- Spinocerebellar ataxia type 1 (SCA 1)
- Spinocerebellar ataxia type 2 (SCA2)
- Spinocerebellar ataxia type 3 (SCA3): clinical features
- Spinocerebellar ataxia type 3 (SCA3): management
- Spinocerebellar ataxia type 4 (SCA4)
- Spinocerebellar ataxia type 5 (SCA5)
- Spinocerebellar ataxia type 6 (SCA6)
- Spinocerebellar ataxia type 7 (SCA7)
- Spinocerebellar ataxia type 8 (SCA8)
- Spinocerebellar ataxia type 9 (SCA9)
- Spinocerebellar ataxia type 10 (SCA10)
- Spinocerebellar ataxia type 11 (SCA11)
- Spinocerebellar ataxia type 12 (SCA12)
- Spinocerebellar ataxia type 13 (SCA13)
- Spinocerebellar ataxia type 14 (SCA14)
- Spinocerebellar ataxia type 15 (SCA15)
- Spinocerebellar ataxia type 16 (SCA16)
- Spinocerebellar ataxia type 17 (SCA17)
- Spinocerebellar ataxia type 18 (SCA18)
- Spinocerebellar ataxia type 19 (SCA19)
- Spinocerebellar ataxia type 20 (SCA20)
- Spinocerebellar ataxia type 21 (SCA21)
- Spinocerebellar ataxia type 22 (SCA22)
- Spinocerebellar ataxia type 23 (SCA23)
- Spinocerebellar ataxia type 24 (SCA24)
