SLIPPERS
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
SLIPPERS. This is supratentorial lymphocytic inflammation with parenchymal enhancement responsive to steroids. Fully referenced neurology checklist.
Pathology
- This is supratentorial lymphocytic inflammation with parenchymal enhancement responsive to steroids
- It is a T-cell medicated perivascular inflammatory disorder
Clinical features
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Course
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Differential diagnosis
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Magnetic resonance imaging (MRI) brain
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Cerebrospinal fluid (CSF) analysis
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Brain biopsy features
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Treatment
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References
- Tsibonakis A, Theodorou A, Korkolopoulou P, Tsivgoulis G. Supratentorial lymphocytic inflammation with parenchymal perivascular enhancement responsive to steroids: a potentially overlooked diagnosis. Ann Neurol 2024; 95:407-409.
- Sudhakar V, Gersey Z, Polster SP, Mantica M, Zenonos G. Supratentorial lymphocytic inflammation with parenchymal perivascular enhancement responsive to steroids: a case report and literature review. Surg Neurol Int 2021; 12:327.
- Khan A, Khan MM, Al-Bozom IA, Baregzai Y, Ibrahim W, Hammadi F. The elusive SLIPPERS Syndrome (supratentorial lymphocytic inflammation with parenchymal perivascular enhancement responsive to steroids): a case report and literature review. Int Med Case Rep J 2023; 16:357-361.
- Freua F, Mahler JV, Lima PLGSB, et al. Supratentorial lymphocytic inflammation with parenchymal perivascular enhancement responsive to steroids (SLIPPERS)-does it really exist? Brain Sci 2023; 13:1191.
- Fahimdanesh K, White J, Tsai M, Cevallos C, Feng J. SLIPPERS syndrome: clinical heterogeneity and management challenges in two case studies. Neurology 2024; 103(Suppl 1): S12-S13.
