Chronic relapsing inflammatory optic neuropathy (CRION)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Chronic relapsing inflammatory optic neuropathy (CRION). CRION presents as a subacute optic neuropathy. Fully referenced neurology checklist.

Clinical features

  • CRION presents as a subacute optic neuropathy
  • It is usually painful
  • It is bilateral but usually sequential
  • It produces a worse visual loss than typical optic neuritis
  • It has a relapsing course

Differential diagnosis of optic neuropathy

Locked: subscribe to see this section.

Magnetic resonance imaging (MRI)

Locked: subscribe to see this section.

Cerebrospinal fluid (CSF)

Locked: subscribe to see this section.

Treatment

Locked: subscribe to see this section.

References

  1. Kidd D, Burton B, Plant GT, Graham EM. Chronic relapsing inflammatory optic neuropathy (CRION). Brain 2003; 126:276-284.
  2. Sharma A, Khurana D, Kesav P. MRI findings in chronic relapsing inflammatory optic neuropathy. BMJ Case Reports 2013. doi:10.1136/bcr-2012-008100.

Related checklists

Loading...