Scans without evidence of dopaminergic deficiency (SWEDDs)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Scans without evidence of dopaminergic deficiency (SWEDDs). Asymmetric resting dystonic tremor, Increased tone. Fully referenced neurology checklist.
Clinical features of SWEDDS
- Asymmetric resting dystonic tremor
- Increased tone
- Impaired arm swing
- Facial hypomimia
- Jaw tremor
- Slow gait with small stride length and reduced arm swing: like in PD
- Dystonic action writing tremor
Differentials of non-tremor dominant (akinetic-rigid) phenotype
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Differentials of tremor dominant phenotype
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SWEDDS v Parkinson’s disease (PD)
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SWEDDS gait v Parkinson’s disease (PD) gait
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Significance of SWEDDs
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References
- Schwingenschuh P, Ruge D, Edwards MJ, et al. Adult onset asymmetric upper limb tremor misdiagnosed as Parkinson's disease: a clinical and electrophysiological study. Mov Disord 2010; 25:560-569.
- Mian OS, Schneider SA, Schwingenschuh P, Bhatia KP, Day BL. Gait in SWEDDs patients: comparison with Parkinson's disease patients and healthy controls. Mov Disord 2011; 26:1266-1273.
- Schirinzi T, Imbriani P, D’Elia A, Bentivoglio AR, Pisani A. Occurrence of writing tremor in patients with scans without evidence of dopaminergic deficit. Move Disord Clin Pract 2015; doi: 10.1002/mdc3.12302 (Epub ahead of issue).
- Bajaj N. SWEDD for the general neurologist. ACNR 2010; 10:30-31.
- Schwingenschuh P, Ruge D, Edwards MJ, et al. Distinguishing SWEDDs patients with asymmetric resting tremor from Parkinson's disease: a clinical and electrophysiological study. Mov Disord 2010; 25:560-569.
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