Rosai-Dorfman disease (RDD): systemic features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Rosai-Dorfman disease (RDD): systemic features. Fever, Weight loss, Fatigue, Night sweats. Fully referenced neurology checklist.

Systemic features

  • Fever
  • Weight loss
  • Fatigue
  • Night sweats
  • Bilateral cervical lymphadenopathy
  • Systemic lymphadenopathy

Gastrointestinal features

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Respiratory features

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Cardiac features

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Ophthalmological features

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Dermatological features

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Haematological features

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Renal features

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Other organ systemic features

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Synonyms

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References

  1. Gilani K, Kuntz S, Munoz DG, Schneider R. Pearls & Oy-sters: Rosai-Dorfman disease of the central nervous system. Neurology 2021 (Online ahead of print). 
  2. Abla O, Jacobsen E, Picarsic J, et al. Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease. Blood 2018; 131:2877-2890.
  3. Alatassi H, Ray MB, Galandiuk S, Sahoo S. Rosai-Dorfman disease of the gastrointestinal tract: report of a case and review of the literature. Int J Surg Pathol 2006; 14:95-99.
  4. Wimmer DB, Ro JY, Lewis A, et al. Extranodal rosai-dorfman disease associated with increased numbers of immunoglobulin g4 plasma cells involving the colon: case report with literature review. Arch Pathol Lab Med 2013; 137:999-1004. 
  5. Poldemann JJ, Hinrichs BH, Makramalla A. Unique presentation of Rosai-Dorfman disease as concomitant appendiceal and rectal masses with IgG4-positive plasma cells diagnosed by core needle biopsy. Case Rep Oncol Med 2020; 2020:8814871.
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