Rosai-Dorfman disease (RDD): management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Rosai-Dorfman disease (RDD): management. Uniformly enhancing dural-based lesions, These may demonstrate a dural tail. Fully referenced neurology checklist.

Magnetic resonance imaging (MRI) brain

  • Uniformly enhancing dural-based lesions
  • These may demonstrate a dural tail
  • There may be associated vasogenic oedema
  • Parenchymal lesions may occur

Cerebrospinal fluid (CSF) analysis

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Blood investigations

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Other investigations

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Treatment

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Synonyms

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References

  1. Varrassi M, Corridore A, Tommasino E, et al. MR imaging of cerebral involvement of Rosai-Dorfman disease: a single-centre experience with review of the literature. Radiol Med 2021; 126:89-98.
  2. Aljohani HT, Robin S. A rare case of isolated intracranial Rosai-Dorfman disease mimicking optic nerve meningioma: a case report and literature review. Asian J Neurosurg 2018; 13:845-847.
  3. Gilani K, Kuntz S, Munoz DG, Schneider R. Pearls & Oy-sters: Rosai-Dorfman disease of the central nervous system. Neurology 2021 (Online ahead of print).
  4. Abla O, Jacobsen E, Picarsic J, et al. Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease. Blood 2018; 131:2877-2890.
  5. Wei C, Zhou DB. Long-time remission of laryngeal Rosai-Dorfman disease with thalidomide: a report of three cases. Hematology 2021; 26:552-555.
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