ROHHAD: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
ROHHAD: management. Adrenocortical insufficiency, Growth hormone (GH) deficiency, Hypothyroidism, Hyperprolactinemia. Fully referenced neurology checklist.
Endocrine investigations
- Adrenocortical insufficiency
- Growth hormone (GH) deficiency
- Hypothyroidism
- Hyperprolactinemia
- Hypernatraemia
- Inappropriate antidiuretic hormone secretion (SIADH)
Cerebrospinal fluid (CSF) analysis
Locked: subscribe to see this section.
Magnetic resonance imaging (MRI) brain
Locked: subscribe to see this section.
Polysomnography
Locked: subscribe to see this section.
Immunosuppression treatment
Locked: subscribe to see this section.
Other treatments
Locked: subscribe to see this section.
Acronym
Locked: subscribe to see this section.
Synonym
Locked: subscribe to see this section.
References
- Ize-Ludlow D, Gray JA, Sperling MA, et al . Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation presenting in childhood. Pediatrics 2007; 120:e179-e188.
- Maksoud I, Kassab L. Rapid-onset obesity, hypoventilation, hypothalamic dysfunction, autonomic dysregulation syndrome. Avicenna J Med 2015; 5:89-94.
- Mandel-Brehm C, Benson LA, Tran B, Kung AF, et al. ZSCAN1 autoantibodies are associated with pediatric paraneoplastic ROHHAD. Ann Neurol 2022; 92:279-291.
- Serafim AB, Olivé-Cirera G, Ortega-González Á, et al. Antibodies against ZSCAN1 in pediatric and adult patients with non-paraneoplastic ROHHAD syndrome. Neurol Neuroimmunol Neuroinflamm 2024; 11:e200276.
- Aljabban L, Kassab L, Bakoura NA, Alsalka MF, Maksoud I.J Rapid-onset obesity, hypoventilation, hypothalamic dysfunction, autonomic dysregulation and neuroendocrine tumor syndrome with a homogenous enlargement of the pituitary gland: a case report. Med Case Rep 2016; 10:328.
- And 5 more. Subscribe to see the full list
