Reversible cerebral vasoconstriction syndrome (RCVS): differential diagnosis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Reversible cerebral vasoconstriction syndrome (RCVS): differential diagnosis. Primary angiitis of the central nervous system (PACNS).

Differential diagnosis

  • Primary angiitis of the central nervous system (PACNS)
  • Posterior reversible encephalopathy syndrome (PRES)
  • Migraine
  • Stroke

Predictors of RCVS against PACNS

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Predictors of PACNS against RCVS

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References

  1. Ducros A, Boukobza M, Porcher R, Sarov M, Valade D, Bousser MG. The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome: a prospective sites of 67 patients. Brain 2007; 130:3091-3101.
  2. Ducros A, Bousser MG. Reversible cerebral vasoconstriction syndrome. Pract Neurol 2009; 9:256-267.
  3. Sattar A, Manousakis G, Jensen MB. Systematic review of reversible cerebral vasoconstriction syndrome. Expert Rev Cardiovasc Ther 2010; 8:1417-1421.
  4. Toljan K, Amin M, Scarsella M, et al. Overlapping features of posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome. J Neurol Sci 2026; 486:125940.
  5. de Boysson H, Parienti JJ, Mawet J, et al. Primary angiitis of the CNS and reversible cerebral vasoconstriction syndrome: a comparative study. Neurology 2018; 91:e1468-e1478. 
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