Reversible cerebral vasoconstriction syndrome (RCVS): causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Reversible cerebral vasoconstriction syndrome (RCVS): causes. Selective serotonin reuptake inhibitors (SSRIs): these account for about 20% of cases.

Antidepressants

  • Selective serotonin reuptake inhibitors (SSRIs): these account for about 20% of cases

Nasal decongestants

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Migraine drugs

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Cytotoxic agents

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Other drugs

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Drugs of abuse

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Medical causes

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Neurosurgical causes

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Other causes

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References

  1. Ducros A, Boukobza M, Porcher R, Sarov M, Valade D, Bousser MG. The clinical and radiological spectrum of reversible cerebral vasoconstriction syndrome: a prospective sites of 67 patients. Brain 2007; 130:3091-3101.
  2. Wang X, Zhang Y, You H, Zhu T, Zhou D. A case of reversible cerebral vasoconstriction syndrome triggered by high-dose methotrexate in a boy with lymphoma. Headache 2019; doi: 10.1111/head.13526 (Epub ahead of print).
  3. Moshe-Lilie O, Miller P, Lane M. A unique case of cabergoline-induced reversible cerebral vasoconstriction. Neurol Clin Pract 2019; 9:536-538. 
  4. Palma JA, Fontes-Villalba A, Irimia P, Garcia-Eulate R, Martinez-Vila E. Reversible cerebral vasoconstriction syndrome induced by adrenaline. Cephalalgia 2012; 32:500-504.
  5. Soo Y, Singhal AB, Leung T, et al. Reversible cerebral vasoconstriction syndrome with posterior reversible leucoencephalopathy after oral contraceptive pills. Cephalalgia 2009; 30:42-45.
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