Recurrent encephalopathy: causes
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Recurrent encephalopathy: causes. Klein-Levin syndrome (KLS), Familial hemiplegic migraine (FHM), Neurosarcoidosis. Fully referenced neurology checklist.
Neurological causes
- Klein-Levin syndrome (KLS)
- Familial hemiplegic migraine (FHM)
- Neurosarcoidosis
- Relapsing encephalopathy with cerebellar ataxia (RECA):
- Aicardi Goutieres syndrome (AGS)
- SCN2A missense mutaion
Vascular causes
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Infective causes
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Metabolic causes
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Endocrine causes
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Systemic causes
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Toxic and drug-induced
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References
- Iqbal M, Prasad M, Ritey C. Recurrent encephalopathy? No I'm a sleeping beauty! J Pediatr Neurosci 2014; 9:82-84.
- Spacey SD, Vanmolkot KR, Murphy C, van den Maagdenberg AM, Hsiung RG. Familial hemiplegic migraine presenting as recurrent encephalopathy in a Native Indian family. Headache 2005; 45:1244-1249.
- Rudkin AK, Wilcox RA, Slee M, Kupa A, Thyagarajan D. Relapsing encephalopathy with headache: an unusual presentation of isolated intracranial neurosarcoidosis. JNNP 2007; 78:770-771.
- Sabouraud P, Riquet A, Spitz MA, et al. Relapsing encephalopathy with cerebellar ataxia are caused by variants involving p.Arg756 in ATP1A3. Eur J Paediatr Neurol 2019; 23:448-455.
- Samanta D, Ramakrishnaiah R. Recurrent encephalopathy with spinal cord involvement: an atypical manifestation of Aicardi-Goutières syndrome. Ann Indian Acad Neurol 2019; 22:111-115.
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