Progressive supranuclear palsy (PSP): differential diagnosis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Progressive supranuclear palsy (PSP): differential diagnosis. Parkinson’s disease (PD). Fully referenced neurology checklist.
Parkinsonian disorders
- Parkinson’s disease (PD)
- Dementia with Lewy bodies (DLB)
- Multiple system atrophy (MSA)
- Corticobasal degeneration (CBD)
- Post encephalitic parkinsonism
- Perry syndrome
- Kufor-Rakeb
- Gaucher’s disease
Mokri syndrome
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Other differentials
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Features against a diagnosis of PSP
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Acronym
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References
- Litvan I, Agid A, Calne D, et al. Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-PSP International Workshop. Neurology 1996; 47:1-9.
- Ling H, Massey LA, Lees AJ, Brown P, Day BL. Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease. Brain 2012; 135:1141-1153.
- Höglinger GU, Respondek G, Stamelou M, et al. Clinical diagnosis of progressive supranuclear palsy: The Movement Disorder Society criteria. Mov Disord 2017; 32:853-864.
- Stamelou M, Quinn NP, Bhatia KP. "Atypical" atypical parkinsonism: new genetic conditions presenting with features of progressive supranuclear palsy, corticobasal degeneration, or multiple system atrophy-a diagnostic guide. Mov Disord 2013; 28:1184-1199.
- Tisel SM, Ahlskog JE, Duffy JR, Matsumoto JY, Josephs KA. PSP-like syndrome after aortic surgery in adults (Mokri syndrome). Neurol Clin Pract 2020; 10:245-254.
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