Primary progressive aphasia (PPA): ALS subtype (PPA-ALS)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Primary progressive aphasia (PPA): ALS subtype (PPA-ALS). Non-fluent variant PPA ALS (nfvPPA-ALS or nfvPA-MND). Fully referenced neurology checklist.
Subtypes
- Non-fluent variant PPA ALS (nfvPPA-ALS or nfvPA-MND)
- Semantic variant PPA MND (svPPA-ALS) or svPA-MND)
Genetics
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Clinical features
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Magnetic resonance imaging (MRI) brain
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Pathology
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Synonym
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References
- Tan RH, Guennewig B, Dobson-Stone C, et al. The underacknowledged PPA-ALS: a unique clinicopathologic subtype with strong heritability. Neurology 2019; 92:e1354-e1366.
- Vinceti G, Olney N, Mandelli ML, et al. Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates. Amyotroph Lateral Scler Frontotemporal Degener 2019; 20:146-158.
