Primary central nervous system lymphoma (PCNSL): MRI features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Primary central nervous system lymphoma (PCNSL): MRI features. PCNSL usually manifests as a single lesion at presentation. The diameter is at least 15mm.

Main MRI features

  • PCNSL usually manifests as a single lesion at presentation
  • The diameter is at least 15mm
  • It is iso-hypointense on T1 weighted
  • It is hypointense on T2
  • The lesion is in contact with subarachnoid space

Other MRI features

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Frequent locations of lesions

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References

  1. Slone HW, Blake JJ, Shah R, Guttikonda S, Bourekas EC. CT and MRI findings of intracranial lymphoma. Am J Roentgenol 2005; 184:1679-1685.
  2. Gavrilovic IT, Abrey LE. Diagnosis and treatment of primary central nervous system lymphoma. Curr Oncol Rep 2005; 7:47-54.
  3. Kuker W, Nagele T, Korfel A, et al. Primary central nervous system lymphomas (PCNSL): MRI features at presentation in 100 patients. J Neuro Oncol 2005; 72:169-177.
  4. Schlegel U. Primary CNS lymphoma. Ther Adv Neurol Disord 2009; 2:93-104.

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