Pregnancy and pituitary adenomas

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Pregnancy and pituitary adenomas. Cushing's disease, Acromegaly, Prolactinoma, TSH-secreting tumours. Fully referenced neurology checklist.

Types of pituitary disorders

  • Cushing's disease
  • Acromegaly
  • Prolactinoma
  • TSH-secreting tumours
  • Gonadotropin-producing tumours
  • Non-functioning adenomas (NFAs)
  • Craniopharyngioma
  • Sheehan's syndrome
  • Hypopituitarism
  • Lymphocytic hypophysitis
  • Pituitary apoplexy

Preconception counselling

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Preconception follow-up

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Preconception medical treatment: prolactinomas

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Preconception medical treatment: acromegaly

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Preconception medical treatment: general

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Preconception surgical treatment

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Monitoring of pregnancy

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Management of tumour progression in pregnancy

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Management of pituitary apoplexy in pregnancy

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Post-partum phase

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References

  1. Klawiter EC, Bove R, Elsone L, et al. High risk of postpartum relapses in neuromyelitis optica spectrum disorder. Neurology 2017; 89:2238-2244.
  2. Karaca Z, Tanriverdi F, Unluhizarci K, Kelestimur F. Pregnancy and pituitary disorders. Eur J Endocrinol 2010; 162:453-475. 
  3. Prager D, Braunstein GD. Pituitary disorders during pregnancy. Endocrinol Metab Clin North Am 1995; 24:1-14.
  4. Jia XY, Guo XP, Yao Y, Deng K, Lian W, Xing B. Surgical management of pituitary adenoma during pregnancy. World J Clin Cases 2023; 11:2694-2707.
  5. Gheorghe AM, Trandafir AI, Stanciu M, Popa FL, Nistor C, Carsote M. Challenges of pituitary apoplexy in pregnancy. J Clin Med 2023; 12:3416.

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