Pregnancy and Parkinson’s disease (PD)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Pregnancy and Parkinson’s disease (PD). Most pregnancies are completed without complications. Fully referenced neurology checklist.
Effect of pregnancy on Parkinson’s disease (PD)
- Most pregnancies are completed without complications
- There are case reports of PD worsening in pregnancy
- PD is not associated with increased foetal or birth complications
- The spontaneous abortion rate is 8-9%
- Depression is the most frequent post-partum complication
Safety of PD drugs in pregnancy
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Management of PD in pregnancy and breastfeeding
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Acronym
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References
- Shulman LM, Minagar A, Weiner WJ. The effect of pregnancy in Parkinson's disease. Mov Disord 2000; 15:132-135.
- Seier M, Hiller A. Parkinson's disease and pregnancy: an updated review. Parkinsonism Relat Disord 2017; 40:11-17.
- Lamichhane D, Narayanan NS, Gonzalez-Alegre P. Two cases of pregnancy in Parkinson's disease. Parkinsonism Relat Disord 2014; 20:239-240.
- Young C, Phillips R, Ebenezer L, Zutt R, Peall KJ. Management of Parkinson's disease during pregnancy: literature review and multidisciplinary input. Mov Disord Clin Pract 2020; 7:419-430.
- Olivola S, Xodo S, Olivola E, Cecchini F, Londero AP, Driul L. Parkinson's disease in pregnancy: a case report and review of the literature. Front Neurol 2020; 10:1349.
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