Posterior cortical atrophy (PCA)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Posterior cortical atrophy (PCA). This is a neurodegenerative disease predominantly involving the occipital and parietal cortex.
Patient profile
- This is a neurodegenerative disease predominantly involving the occipital and parietal cortex
- It is usually associated with Alzheimer’s disease (AD)
- The onset age is in the 50’s and early 60’s
- Women are affected twice as often as men
Functional visual difficulties
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Visual features
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Cognitive features
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Associated cortical syndromes
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Systemic symptoms
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Types of pathology
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Investigations
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Treatment
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Synonym
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References
- Husain M. Components of posterior cortical atrophy. JNNP 2012; 83:855.
- McMonagle P, Deering F, Berliner Y, Kertesz A. The cognitive profile of posterior cortical atrophy. Neurology 2006; 66:331-338.
- Tang-Wai DF, Graff-Radford NR, Boeve BF, et al. Clinical, genetic, and neuropathologic characteristics of posterior cortical atrophy. Neurology 2004; 63:1168-1174.
- Crutch SJ, Lehmann M, Schott JM, Rabinovici GD, Rossor MN, Fox NC. Posterior cortical atrophy. Lancet Neurol 2012; 11:170-178.
- Zakzanis VK, Boulos MI. Posterior cortical atrophy. Neurologist 2001; 7:341–349.
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