Post-radiation lower motor neurone syndrome (PRLMNS)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Post-radiation lower motor neurone syndrome (PRLMNS). This is possibly a lumbosacral radiculopathy. Fully referenced neurology checklist.

Pathology

  • This is possibly a lumbosacral radiculopathy
  • The onset is 9-14 years after radiation treatment

Reasons for radiation therapy

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Clinical features

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Differential diagnosis

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Investigations

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References

  1. Bowen J, Gregory R, Squier M, Donaghy M. The post-irradiation lower motor neuron syndrome neuronopathy or radiculopathy? Brain 1996; 119:1429-1439.
  2. Abraham A, Drory VE. Postradiation lower motor neuron syndrome: case series and literature review. J Neurol 2013; 260:1802-1806.
  3. van der Sluis RW, Wolfe GI, Nations SP, et al. Post-radiation lower motor neuron syndrome. J Clin Neuromuscul Dis 2000; 2:10-17.
  4. Lamy C, Mas JL, Varet B, Ziegler M, de Recondo J. Postradiation lower motor neuron syndrome presenting as monomelic amyotrophy. JNNP 1991; 54:648-649.
  5. Jackson M. Post radiation monomelic amyotrophy. JNNP 1992; 55:629.

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