Hopkins syndrome
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Hopkins syndrome. This is flaccid paralysis associated with asthmatic attacks. Fully referenced neurology checklist.
Pathology
- This is flaccid paralysis associated with asthmatic attacks
- The onset is about a week after an acute asthma attack
Causes
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Clinical features
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Differential diagnosis
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Magnetic resonance imaging (MRI) spine: features
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Electromyogram (EMG): features
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Muscle biopsy
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Normal investigations
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Treatment
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Synonym
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References
- Kumar P, Kumar P, RY K. Monocrural flaccid paralysis following asthmatic attack (post asthmatic amyotrophy) - case report & minireview. Clin Neurol Neurosurg 2014; 123:1-3.
- Souza PVS, Badia BML, Gonçalves EA, et al. Teaching NeuroImages: Hopkins syndrome: a rare differential diagnosis of neurogenic monomelic amyotrophy. Neurology 2020; 94:e996-e997.
- Liedholm LJ, Eeg-Olofsson O, Ekenberg BE, Nicolaysen RB, Torbergsen T. Acute postasthmatic amyotrophy (Hopkins' syndrome). Muscle Nerve 1994; 17:769-772.
- Hayashi F, Hayashi S, Matsuse D, Yamasaki R, Yonekura K, Kira JI. Hopkins syndrome following the first episode of bronchial asthma associated with enterovirus D68: a case report. BMC Neurol 2018; 18:71.
- Shahar EM, Hwang PA, Niesen CE, Murphy EG. Poliomyelitis-like paralysis during recovery from acute bronchial asthma: possible etiology and risk factors. Pediatrics 1991; 88:276-279.
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